ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Killer cell lectin-like receptor 3

Intermolecular
Cysteine 149 and cysteine 149
Intramolecular
Cysteine 149 and cysteine 154
A redox-regulated disulphide may form between two units of Killer cell lectin-like receptor 3 at cysteines 149 and 149.

Details

Redox score ?
69
PDB code
5j6g
Structure name
recognition of the mhc class ib molecule h2-q10 by the natural killer cell receptor ly49c
Structure deposition date
2016-04-04
Thiol separation (Å)
5
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide A name
Killer cell lectin-like receptor 3
Peptide B name
Killer cell lectin-like receptor 3
Peptide A accession
Q64329
Peptide B accession
Q64329
Peptide A residue number
149
Peptide B residue number
149

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Killer cell lectin-like receptor 3 between cysteines 149 and 154 (145 and 150 respectively in this structure).

Details

Redox score ?
83
PDB code
3c8j
Structure name
the crystal structure of natural killer cell receptor ly49c
Structure deposition date
2008-02-12
Thiol separation (Å)
2
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q61198
Residue number A
149
Residue number B
154
Peptide name
Killer cell lectin-like receptor 3

Ligandability

Cysteine 149 of Killer cell lectin-like receptor 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 154 of Killer cell lectin-like receptor 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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